Transdermal rotigotine in early stage Parkinson's disease: a randomized, double-blind, placebo-controlled trial.
Identifieur interne : 000719 ( Main/Exploration ); précédent : 000718; suivant : 000720Transdermal rotigotine in early stage Parkinson's disease: a randomized, double-blind, placebo-controlled trial.
Auteurs : Yoshikuni Mizuno [Japon] ; Masahiro Nomoto ; Tomoyoshi Kondo ; Kazuko Hasegawa ; Miho Murata ; Masahiro Takeuchi ; Junji Ikeda ; Takayuki Tomida ; Nobutaka HattoriSource :
- Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2013.
English descriptors
- KwdEn :
- Administration, Cutaneous, Age Factors, Aged, Antiparkinson Agents (administration & dosage), Antiparkinson Agents (adverse effects), Antiparkinson Agents (therapeutic use), Disease Progression, Double-Blind Method, Endpoint Determination, Female, Humans, Male, Middle Aged, Parkinson Disease (drug therapy), Tetrahydronaphthalenes (administration & dosage), Tetrahydronaphthalenes (adverse effects), Tetrahydronaphthalenes (therapeutic use), Thiophenes (administration & dosage), Thiophenes (adverse effects), Thiophenes (therapeutic use).
- MESH :
- chemical , administration & dosage : Antiparkinson Agents, Tetrahydronaphthalenes, Thiophenes.
- chemical , adverse effects : Antiparkinson Agents, Tetrahydronaphthalenes, Thiophenes.
- chemical , therapeutic use : Antiparkinson Agents, Tetrahydronaphthalenes, Thiophenes.
- drug therapy : Parkinson Disease.
- Administration, Cutaneous, Age Factors, Aged, Disease Progression, Double-Blind Method, Endpoint Determination, Female, Humans, Male, Middle Aged.
Abstract
We conducted a randomized, double-blind, placebo-controlled trial to determine the safety and efficacy of transdermal rotigotine at doses up to 16 mg/24 hours in patients with early stage Parkinson's disease (PD) in Japan.
DOI: 10.1002/mds.25537
PubMed: 23801585
Affiliations:
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Le document en format XML
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<author><name sortKey="Tomida, Takayuki" sort="Tomida, Takayuki" uniqKey="Tomida T" first="Takayuki" last="Tomida">Takayuki Tomida</name>
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<series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title>
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<front><div type="abstract" xml:lang="en">We conducted a randomized, double-blind, placebo-controlled trial to determine the safety and efficacy of transdermal rotigotine at doses up to 16 mg/24 hours in patients with early stage Parkinson's disease (PD) in Japan.</div>
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<tree><noCountry><name sortKey="Hasegawa, Kazuko" sort="Hasegawa, Kazuko" uniqKey="Hasegawa K" first="Kazuko" last="Hasegawa">Kazuko Hasegawa</name>
<name sortKey="Hattori, Nobutaka" sort="Hattori, Nobutaka" uniqKey="Hattori N" first="Nobutaka" last="Hattori">Nobutaka Hattori</name>
<name sortKey="Ikeda, Junji" sort="Ikeda, Junji" uniqKey="Ikeda J" first="Junji" last="Ikeda">Junji Ikeda</name>
<name sortKey="Kondo, Tomoyoshi" sort="Kondo, Tomoyoshi" uniqKey="Kondo T" first="Tomoyoshi" last="Kondo">Tomoyoshi Kondo</name>
<name sortKey="Murata, Miho" sort="Murata, Miho" uniqKey="Murata M" first="Miho" last="Murata">Miho Murata</name>
<name sortKey="Nomoto, Masahiro" sort="Nomoto, Masahiro" uniqKey="Nomoto M" first="Masahiro" last="Nomoto">Masahiro Nomoto</name>
<name sortKey="Takeuchi, Masahiro" sort="Takeuchi, Masahiro" uniqKey="Takeuchi M" first="Masahiro" last="Takeuchi">Masahiro Takeuchi</name>
<name sortKey="Tomida, Takayuki" sort="Tomida, Takayuki" uniqKey="Tomida T" first="Takayuki" last="Tomida">Takayuki Tomida</name>
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<country name="Japon"><noRegion><name sortKey="Mizuno, Yoshikuni" sort="Mizuno, Yoshikuni" uniqKey="Mizuno Y" first="Yoshikuni" last="Mizuno">Yoshikuni Mizuno</name>
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